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Thanks, this was an article I had not seen. It would make sense just to add a lower dose arm to the ongoing trials. I think there is a possibility I am on the placebo, so I would like to see a re-randomization where I would either get .5mg or the lower dose. Sounds more ethical to me!

Green light today for FTY 720 approval.

http://online.wsj.com/article/BT-CO-201 ... inesEurope

It's been 21/2 months now since I swallowed the pink pill. I'm driving myself crazy trying to figure out if I'm actually on the drug or not. My neuro said to expect changes 3-6 months after the first dose so it's a little too early to tell. I have had one abnormal blood test --- cholesterol and mild...

Hi KateCW,

I tried 4AP for 30 days and did not notice a change in my slow, awkward gait, so I stopped. I'm not sure why it did not work on me but I
would not hesitate to try it.

Good news for FTY 720. After halting the study for primary progressive patients last fall, Novartis has re-opened enrollment. I was scheduled for the screening to enter the trial today. Yea!

Hi Astrid and others following the FTY 720 trial for PPMS, I was contacted yesterday via e-mail by my neurologist's office and told that Novartis has put a halt on screening any new participants for this trial globally. Wonder why? I hope it is because the drug works and Novartis anticipates being a...

Cooking, cleaning and laundry is rough most days. Both my kids, especially the older helps. He likes to eat so he is learning to cook! It makes sense that information has to be held from trial participants as well as trial doctors. As long as the results are being monitored for safety I guess we hav...

Hi Astrid and Rob, I was diagnosed with PPMS Nov. 2006 and currently scheduled to enter the FTY 720 trial for PPMS in the second week of Nov. 2009. I have faced many delays in the last six months due to finalizing of the protocol and rules and regulations of the study site in Charlotte, NC. I know n...

I had been given the paper work for the 1.25mg vs placebo trial but had not signed it. My understanding is that the original trial continues as is with most of the already enrolled participants in Canada. The original trial answers the question: Is FTY720 effective in PPMS? The new trial answers the...

May 20th was the date I was scheduled to enter the FTY 720 trial for PPMS patients with an intensive day of screening tests. I was trying not to be too hopeful about it because it is 1.25 mg vs placebo. (50-50 chance). I had arranged my ride, scheduled the time off work and started worrying about my...

Wow is right. All I know is ---- you will help your doctors figure it out. From my first forum encounter with your story I was always uncomfortable with your clear spinal tap. Our clinical presentations were similar. At age 42, I began having right arm weakness and right leg weakness. I have two non...

Carole, you have truly been an inspiration to me! You have helped me to be realistic with my expectations as I enter the trial. I was supposed to have my screenings this week but the trial coordinator said things have been postponed due to paperwork. They have hinted it has something to do with the ...

I recently encountered a local well-known MS Expert (not my own neuro) who was adamant about wanting me to try IV steroids, then Tysabri if I had a positive response to the steroids. He pretty much told me my own neuro, another well known expert in this state was wrong to treat me with antibiotics, ...

It is a great idea but I doubt the incentive to push for new research with new ideas would be as great. Money unfortunately is a great motivator ....

http://www.breitbart.com/article.php?id=CNG.e67f6ceac8d2d7ee544d913d28fedcc9.1231&show_article=1 Stem cells transplanted into early-phase multiple sclerosis patients stabilised, and in some cases reversed, the debilitating neurological disorder, according to a study published Friday. Multiple sc...