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Dementia risks with anticholinergic medications

Posted: Wed Dec 15, 2021 2:27 pm
by NHE
Many medications that MS patients take, e.g., baclofen and tizanidine, contain drugs that have been reported to have anticholinergic activity. In effect, they inhibit the neurotransmitter acetylcholine. Repeated usage can cause mental fogginess, increase the risks of dementia and increase brain atrophy. The risks of deleterious side effects increase when these drugs are taken in combination and/or used over an extended period.

Here are some articles that discuss the issue in further detail.